Polynucleotide Chains
DNA polymerases catalyze the production of polynucleotide chains. Which of the following statements holds true:
A. DNA polymerases do not require a primer in order to initiate the reaction.
B. DNA polymerases require a primer with a free 5'-end.
C. DNA polymerases require a primer base-paired to the template with a free 5'-end.
D. DNA polymerases require a RNA primer base-paired to the template and with a free 3'-end.
E. DNA polymerases require a DNA primer base-paired to the template and with a free 5'-end.
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