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Friday, January 19, 2018


[Morning Rounds by Megan Thielking]


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Welcome to Friday, folks! Here's what you need to know about health and science this morning.


What will a shutdown mean for health care and research?

The Senate is slated to vote today on a bill to keep the government open before federal funding runs out at midnight. Last night, the House passed a measure that would keep the government up and running for the next 30 days and would have funded the Children's Health Insurance Program for six years. But with uncertain support in the Senate, a shutdown could be coming.

If the government does shut down, the FDA would likely have to forgo updating mislabeled medications or conducting routine food safety inspections. The CDC would likely have to furlough staffers during a particularly severe flu season<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=7f1e8689d3&e=4aad33fd68>. The NIH, which might have to hit the brakes on enrollment in clinical trials<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=e75003bac0&e=4aad33fd68>, is scrambling<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=7013a9bf39&e=4aad33fd68> to come up with a plan. And on top of that, all of the government's health agencies would be hamstrung in the effort to combat the opioid crisis. STAT's Erin Mershon and Ike Swetlitz have more here<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=1c129ee869&e=4aad33fd68>.


Trump is addressing anti-abortion activists at today's March for Life

Thousands of anti-abortion activists will take to the streets today for the annual March for Life — and this year, they’ll be joined by the president. President Trump will become the first sitting president to address the rally by satellite since the first march in 1974. The president has taken a firm stance against abortion during his first year in office, including reinstating and expanding<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=5c8113efea&e=4aad33fd68> a policy that prevents foreign aid groups that perform or promote abortions from receiving federal funding.

Trump's speech comes after HHS announced plans for a new office to protect the religious rights of health care providers who oppose gender confirmation surgery, abortion, and other medical services. Critics say it’s possible the move will undercut a woman’s right to abortion or access to contraception and could make it easier for medical professionals to discriminate against patients who are transgender.


ADHD prescriptions are soaring among young women

[87396691-e5ca-4560-8a09-e04a5b7a5bdb.png]

The number of privately insured women ages 25 to 29 in the U.S. who filled a prescription for an ADHD drug jumped a whopping 700 percent between 2003 and 2015, according to a new analysis<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=07467fdca1&e=4aad33fd68> published by the CDC. Those increases were seen across age groups — roughly 4 percent of women between ages 15 and 44 picked up an ADHD prescription in 2015. The most commonly filled prescriptions: Adderall, Vyvanse, and Ritalin.

And while the authors of the new report don’t venture a guess about what’s driving the increase, they say the trend is particularly troubling because there’s so little information available about whether it’s safe to take ADHD drugs during pregnancy. Given that half of all pregnancies in the U.S. aren’t planned, health officials are concerned a growing number of women might be taking the medicines before realizing they’re pregnant. For more on the uncertainty pregnant women and their doctors face in deciding what medications are safe, read this<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=8fcef1a901&e=4aad33fd68>.


Inside STAT<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=1e860fb017&e=4aad33fd68>: Experts clash over exercise benefits

Last month, the American Academy of Neurology said<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=095f03ade8&e=4aad33fd68> for the first time that neurologists “should recommend regular exercise” for patients with mild cognitive impairment, which affects memory, thinking, and judgment. But just nine days earlier, researchers who examined 262 studies on the possible brain benefits of exercise concluded<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=c80f6b57d3&e=4aad33fd68> that empirical support is woefully “insufficient” for claims that exercise can prevent MCI or dementia. The clash sheds light on deep differences between equally respected experts about what kind of proof is needed to back up a public health recommendation. STAT’s Sharon Begley has the story here<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=e5377f6a15&e=4aad33fd68>.


Yemen's health facilities are running low on supplies

More than half of health facilities in Yemen are still shuttered or only partially functional, and many of those that are still open are running dangerously low on drugs and medical supplies. The World Health Organization delivered 200 tons of health supplies to the war-torn country this week. The agency says it's working with other groups and local health care officials on the ground to prevent Yemen’s health system from completely collapsing amid conflict. The country has been devastated by malnutrition and a cholera outbreak that has topped more than one million suspected cases.


Scientists use 3-D printing to create drugs on demand

Chemical engineers have created a 3-D printing approach that might one day be used to manufacture medicine on demand and for relatively little money. Researchers at the University of Glasgow came up<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=aef7dbeddf&e=4aad33fd68> with a software program that details the exact steps needed to produce a certain drug — in this case, a muscle relaxant called baclofen — and then 3-D printed a plastic tray that perfectly controlled the various stages of that reaction. If researchers can overcome the big hurdles to creating and using this kind of system, including good quality control, it could offer a new way to manufacture drugs locally in the future.


What to read around the web today
§  When states add paperwork, even eligible people lose Medicaid. New York Times<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=65d69f7af6&e=4aad33fd68>
§  Trump again targets drug policy office, proposing 95 percent budget cut. Politico<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=5621c15072&e=4aad33fd68>
§  Home care agencies often wrongly deny Medicare to help the chronically ill. Kaiser Health News<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=700e751c35&e=4aad33fd68>


More reads from STAT
§  Angered by high prices and shortages, hospitals will form their own generic drug maker<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=79279bb3e0&e=4aad33fd68>.
§  AIDS activist Mathilde Krim saved my life<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=c0eb7887e4&e=4aad33fd68>.


The latest from STAT Plus
§  Testing the tests: If two liquid biopsies<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=c7ca9feacd&e=4aad33fd68> deliver different results, can they both be right?
§  Key House Republican seeks changes in right-to-try legislation<https://statnews.us11.list-manage.com/track/click?u=f8609630ae206654824f897b6&id=a621f7e8c8&e=4aad33fd68>.




Thanks for reading! Have a wonderful weekend,
[Megan]







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