Characteristics of Histones

Histones are a kind of protein that is known to play a very important role in packaging DNA into chromatin. What of the following characteristics about histones is true?

A. They are responsible for the methylation of DNA and switching on and off of genes.

B. They are responsible for the supercoiling of DNA.

C. They interact with DNA through covalent interactions.

D. An octet of histones and a length of DNA forms a helix.

E. They are responsible for helping topoisomerases bind to the DNA.

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