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February 2018, Week 4

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Kemile A Jackson <[log in to unmask]>
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Fri, 23 Feb 2018 15:20:59 +0000
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Nucleophilic Acyl Substitution

Which of the following statements is correct regarding nucleophilic acyl substitution?

A. Protonation of the carbonyl is followed immediately by loss of the leaving group.

B. SN2 reaction is the primary mechanism for this reaction.1

C. Ester hydrolysis proceeds in a single, concerted step.

D. Loss of the leaving group is followed by carbocation rearrangement.

E. Addition of a nucleophile to the carbonyl is followed by loss of the leaving group.

To see the solution and images, visit the following link:
http://datquestionoftheday.com/organic-chemistry/nucleophilic-acyl-substitution/<https://datquestionoftheday.us4.list-manage.com/track/click?u=d3318065969b7c08ead5d4c4d&id=bc2a96c534&e=61d7ba7392>
















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